9th Mar 2018
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Scientists are creating a pill that could replace exercise
man taking pills at the gym

It goes without saying that exercise is beneficial for all manner of physical, emotional and mental aspects of life.

But many struggle to find the time to get in a few laps of the oval or the pool, lift some weights and get in the necessary exercise to ensure wellbeing.

With this in mind, scientists at Salk Institute for Biological Studies in California are developing a ‘miracle’ medicine called 516 that may one day replace the actual act of exercising.

Lead researcher Ronald Evans claims that 516 is “exercise in a pill”.

The team has been working on the chemical compound 516 for almost 10 years. It works by ‘tricking’ your body into breaking down fat instead of carbohydrates and mimicking the effects of high-performance exercise.

Exercise is the trigger for a chemical process at the molecular level that burns calories and builds muscle. The pill mimics this molecular effect without the need for actual exercise.

This may sound like the lazy man’s way out of exercising, but the truth is that not all people can physically exercise. Older people, people with disabilities, mobility issues, bad backs, chronic pain and other physical ailments often deteriorate both physically and mentally because they cannot exercise. The 516 pill could mean that they have all the benefits of exercise, including building muscle, strengthening their bodies and maintaining a healthy weight.

The drug is still in its trial stages and has had its share of hiccups. Early studies on mice showed that a stronger form of the drug caused cancer.

But 516 isn’t the only exercise pill being developed. There’s another called Compound 14 that fools your body into breaking down sugar by making your cells think they’ve run out of energy.

Compound 14 may help those with diabetes and obesity, although it is far from the testing stages.

On the other hand, there are experimental versions of 516 available now, with bodybuilders and athletes using it, although the substance has been banned by the World Anti-Doping Agency prior to FDA approval.

516 is still a while away from your pharmacy, so until then, the only way to reap the benefits of exercise is to, well, exercise.

Read more at www.salk.edu

Would 516 benefit you or someone you know? Or would you rather all the benefits of exercise the natural way?

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    COMMENTS

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    OnlyGenuineRainey
    11th Mar 2018
    7:03am
    What a waste of research dollars - inventing something that will harm health, harm society, and have potentially devastating consequences for the idiots who use it.
    Sen.Cit.89
    12th Mar 2018
    10:16am
    OGN, That is a despicable comment classifying all the people who may benefit from the 'Pill' as Idiots.
    You obviously consider yourself more knowledgeable than the
    scientists at Salk Institute for Biological Studies in California
    Rosret
    12th Mar 2018
    11:22am
    Sen.Cit.89 he may not be more knowledgeable but I suggest he is wiser.
    It may have the obvious benefits but it would have to be VERY strictly monitored.
    People love to look thin and will do all sorts of terrible things to achieve that goal. We need to go back to the source of the obesity crisis and start there or its just going to be a never ending cycle.
    OnlyGenuineRainey
    12th Mar 2018
    5:14pm
    Sen.Sit89, the brilliant scientists once thought Thalidomide was safe and Marijuana had no benefit and should be banned. Sorry, I'm not claiming to be ''more knowledgeable'', but I've got enough common sense to know taking a pill instead of exercising is NOT a good idea.
    Tib
    12th Mar 2018
    5:39pm
    Rainey I agree with you. I've agreed with you and Rosret today, I'm going to have a little lay down.
    Polly Esther
    13th Mar 2018
    10:12am
    This sounds fantastic. Now all we need is a pill to be invented to combat stupidity :-))
    musicveg
    13th Mar 2018
    12:47pm
    I agree with OGR, it is just another way for someone to make money whilst harming people. They already admitted it cause cancer in mice at high dosage, which will mean over the years it will cause cancer anyway at small dosages as it will accumulate.
    Phyl.
    12th Mar 2018
    10:45am
    Sounds a great idea. So many Athletes and people who 'pound the pavement' end up with knee, hip etc replacements, so perhaps less physical, plus the pill might be a great compromise.
    KSS
    12th Mar 2018
    12:19pm
    Actually Phyl it is a myth that people who 'pound the pavements' end up with hip and knee replacements. In actual fact they have fewer of both compared to the sedentary lot on the couch at home. And there are far more benefits from 'pounding the pavements' too both mental as well as physical.
    Maggie
    14th Mar 2018
    8:45am
    It would be interesting to see your evidence for this.
    Rosret
    12th Mar 2018
    11:17am
    Anorexic girls everywhere. Great pill! How many deaths will this pill cause.
    Star Trekker
    12th Mar 2018
    11:24am
    Should be by prescription only.
    KSS
    12th Mar 2018
    12:25pm
    And anorexic boys Rosret!
    KSS
    12th Mar 2018
    12:26pm
    I agree Star Trecker and only for certain conditions.
    Tib
    12th Mar 2018
    12:47pm
    KSS very few boys have problems with anorexia. I agree with Rosret on this one.
    KSS
    13th Mar 2018
    8:25am
    Tib you might be surprised to learn that 25% of eating disorders are in boys - and fewer get treated.

    "While eating disorders are often portrayed as illnesses that only affect females, large population studies suggest that up to a quarter of people suffering with anorexia nervosa or bulimia nervosa are male, and almost an equal number of males and females suffer with binge eating disorder. We also know that under-diagnosis and cultural stigma mean that the actual proportion of males with eating disorders could be much higher.

    Eating disorders can develop at any age but males and females are most at risk for anorexia nervosa and bulimia nervosa in their late teens/early twenties, while binge eating disorder is more prevalent in a person in their mid-twenties."

    http://www.nedc.com.au/eating-disorders-in-males
    Tib
    13th Mar 2018
    8:46am
    KSS I suspect it's mostly gay males. But you never know with this generation.
    Tib
    13th Mar 2018
    9:21am
    KSS by the way it's not just the cultural stigma that prevents makes getting help especially when it comes to mental health. The whole system is skewed to support females. I recently made mention of male suicde the reaction was typical, men and women both commit suicide but men are better at it. Which completely ignores the fact that 2500 males commit suicide to 700 females. If this was the other way round women would claim it's a gender issue and men wouldnt see a cent.
    Tib
    13th Mar 2018
    9:25am
    Males not makes damn spell check.
    KSS
    14th Mar 2018
    7:40am
    Why mostly 'gay' males?

    You are not correct of course but I just wondered why you thought that.
    Star Trekker
    12th Mar 2018
    11:23am
    I think this "Pill" is a great idea. My daughter & I cannot exercise due to genetic conditions & medication which causes weight gain. Even if we were able to exercise to reduce weight, the medication would put it all back on. Adding one more pill to the cocktail of drugs we are on would not be an issue. The only problem would be the risk of drug interactions & the cancer.
    Charlie
    12th Mar 2018
    12:11pm
    Must have a hell of a fizz to it.
    Tib
    12th Mar 2018
    12:44pm
    I suspect it will have limited use. It may also prove to be dangerous. I'll pass on it.
    disillusioned
    12th Mar 2018
    3:28pm
    Does the pill strengthen weight bearing muscles as well? It seems to me that without exercise the muscles holding our bones together will only get weaker with age. Although I'm not mad on exercise, I can certainly see the difference even 2 gym sessions per week make to my agility, so I think I'll keep off that pill and stick to my exercise routine.
    Phyl.
    12th Mar 2018
    7:36pm
    I would not think it is meant for every person, but surely there are some it would be amazing for.
    Old Man
    12th Mar 2018
    8:19pm
    Geez people, read the article. We may all be dead by the time this is available to the general public. I don't comment on hypotheticals.
    musicveg
    13th Mar 2018
    12:49pm
    The pharmaceutical companies will not stop at nothing. Prevention is the best cure.
    Johnny
    14th Mar 2018
    8:29am
    Perhaps I need a pill to eradicate all the tablets I am taking.
    Phyl.
    14th Mar 2018
    12:45pm
    You have hit the nail on the head Johnny. That would be good for many of us :)
    michele
    16th Mar 2018
    4:45pm
    i would love this pill im a chronic pain sufferer and would definetely benefit from it cant wait hope its not too expensive though


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