Ageing Australians accidentally overdosing on common drug

methotrexate

Since 2000, there have been 22 deaths resulting from overdoses of a drug commonly used to treat rheumatoid arthritis (RI), psoriasis and inflammatory bowel disease (IBS) – all of which could have been avoided.

Methotrexate, which is prescribed in 50-tablet lots that should last a patient one year, is the culprit responsible for these avoidable deaths.

According Dr Rose Cairns, lead researcher and senior poisons specialist at the New South Wales Poisons Information Centre (NSW PIC), "It's so easy to take too much. Patients confuse their weekly dose of methotrexate with their daily medications, and it only take three days for the effect to be lethal."

A study conducted by NSW PIC has found that methotrexate is often mistaken for folic acid tablets, which are often prescribed in conjunction with methotrexate or prednisone. Patients have accidentally overdosed thinking that their RI meds were folic acid tablets. NSW PIC is worried that the number of overdoses will rise along with our ageing population. The age of patients who have overdoses are between 66 to 87 and have generally been attributed to confusion, memory problems, age-related cognitive decline and poor eyesight.

Researchers have recommended changing the way the drug is packaged, from one year’s supply to enough for one month at a time. They’ve also suggested packaging the drug with folic acid similarly to how the oral contraceptive pill is packaged.

"This would make it nearly impossible to make these kinds of errors," said Dr Cairns.

Read more at The Age

7 comments

The overdoses have generally been attributed to "confusion, memory problems, age-related cognitive decline and poor eyesight". What about euthanasia?

It amazes me how easily some doctors will prescibe medications i.e. warfarin being just one example - to very elderly people who often live alone.....And yes in many instances do suffer from things like confusion, memory problems, poor eyesight etc. etc. etc. 

Personally think they should check that some medications taken by elderly people are taken under supervision and check that this supervision is in place...

There is possibly fault with the way this medication is packaged and most likely there are ways to remedy that.

But taking in the points raised by Robi and Shetso1 I do not think the number of fatalaties over the period of 16 years is excessive.

No not excessive yet Gerry but with the media advertising its benefits it might become so. I have certainly taken note should the time ever come when I am looking for my way out. Developing RA, psoriasis or IBS first could be a problem. Wonder if there is a black market?

Sadly it is so easy to over dose on these medications, especially if someone is on other

meds too, which have to be taken daily.  I took myself off methotrexate as I was not

happy with what I read up about it.  

There are 2 things that come to mind, that may help overcome this confusion.

 

1.      Get the Company to change the colours on the packaging. Something bright maybe?

 

2.       If the person has lots of tablets to take, or even just a few,  see their Pharmacist to start putting

          their tablets into a WEB Pack. I don't think this costs a lot of money.  The Pharmacist will pack 

          them  in the order they need to be taken.  This has help thousands of people with confusion etc.

           who live alone with no one to help them.

i wonder if given the age and health of these people some might be taking the only way out they can

I agree with Robi. We have Nothing like Dignitas in Australia like Switzerland has. Problem with this Medication possibly is to Beware some friends and relatives whom can't be trusted.

7 comments



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