Indigenous musician Dr G Yunupingu has died aged 46.

Born blind, the singer-songwriter from Elcho Island became the highest-selling Indigenous artist in history, selling more than half a million copies of his albums, which were sung in a mix of Yolngu and English.

He died at the Royal Darwin Hospital on Tuesday. He had been battling chronic liver and kidney-related problems for years.

Dr Yunupingu was once described as "the greatest voice this continent has ever recorded" and toured across the world, playing for audiences that included former US President Barack Obama, the Pope and Queen Elizabeth II.

Due to cultural sensitivities we have not included a full image or the first name of Dr Yunupingu.

Have you ever seen Dr Yunupingu in concert? Share your favourite songs and memories in the comments.

Read more at the smh.com.au