Midlife obesity linked to Alzheimer’s

Midlife obesity has been linked to an increased risk of developing Alzheimer’s.

Midlife obesity linked to Alzheimer’s

Results of a new study have been released which show that being obese or overweight in middle age leads to an increased risk of developing Alzheimer’s disease.

The National Institute on Aging (NIH), worked with volunteers who participated in the Baltimore Longitudinal Study of Aging (BLSA), in one of the longest running studies into the effects of ageing ever undertaken in North America.

The study, led by Madhav Thambisetty, explored the relationship between weight, as measured by body mass index (BMI) at age 50, and Alzheimer’s disease. It discovered that being obese or overweight at midlife may lead to the onset of dementia at an earlier age than if patients were of a healthy weight.

Of the 1394 BLSA volunteers who participated, more than 10 per cent developed Alzheimer’s. Volunteers were cognitively healthy at the commencement of the study and they underwent cognitive testing every two years for 14 years.

For each unit increase in BMI at age 50, the onset of Alzheimer’s symptoms were accelerated by nearly 7 months for those who eventually developed the degenerative disorder.

Higher midlife BMI was also correlated to higher levels of neurofibrillary tangles, which is an indicator of the disease, even for those who do not develop the condition.

It also showed that those with higher midlife BMI had more amyloid deposits in the region of the brain that often shows the earliest signs of dementia.

Although researchers admit that further studies are required to pinpoint the relationship between BMI at midlife and Alzheimer’s onset, these findings do suggest that maintaining a healthy weight, especially at midlife, may be a way to delay the onset of Alzheimer’s

Read more about this at www.nia.nih.gov

So, what’s new? We’re all aware that being overweight is bad for your health, but now it’s been proven to negatively affect your mental health as well. Do you watch your weight? If not, will the results of this study encourage to you to be more mindful of your midsection and, consequently, your mind?

Watch this video explaining this study.


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    11th Sep 2015
    Dementia is directed related to genes and brain function. Obesity is always a negative factor in our lives. Let us all keep active in body, mind and spirit. Foodwise: sticking to fruit, vegs, quality carbs/flours and reducing processed food of all sorts will only contribute to our Lifestyle. Enjoy!
    Nan Norma
    11th Sep 2015
    MILA is right, obesity is always a negative factor in our lives. The only people I knew with demantia were both thin.
    11th Sep 2015
    Anxiety and stress will accelerate decline in health faster than any other condition..and as life now gives us new things to worry the life out of us every day , I will just continue to journey forward with a positive outlook and my few extra pounds and hope I make it to a grand old age...and stay healthy along the way..
    11th Sep 2015
    From my observations of people close to me who developed dementia,stress was the culprit & their inability to handle it.
    11th Sep 2015
    Yes I have worked in a Dementia Ward and most there had some form of high stress during their life that they had difficulty dealing with. So work on changing the things we can change and accept the things we can not. Only two things are for certain - Taxes and Death - so lets move forward and do the best we can with what we have. Both my parents had the big D in the end, so everyone wish me well please.

    11th Sep 2015
    Well, if that is the case there are going to be an awful lot of people getting Alzheimers.

    When we go shopping at our local shopping centre the number of overweight people is very noticeable.
    Swinging voter
    11th Sep 2015
    Everything is linked to everything these days. The news has become a repetitive daily health information service. Every evening/morning/afternoon we are treated to which disease to expect next. Every "cure" is predicted to happen in five years. I've been waiting about 20 years for at least 20 "cures" previously promised. Even people who have never smoked and are trying to recover from cancer are humiliated and distressed by those quit ads. I know people who never smoked but still got lung or one of the highly graphic cancers warned about on those ads, and they are quite upset about that. We get statistics too: 1 in 10 will get this, 3 our of 4 will get that, 2 out of 10 will this, 1 in 12 will get that....which sounds like out of every 12 people, about 30 shouldn't even be here. We should all get on with life whilst trying to avoid the medical industry putting the fear of God up us every five minutes.
    Tom Tank
    11th Sep 2015
    The use of BMI as an indicator of obesity has been discredited in recent times. It is a simplistic method that does not distinguish between fat and muscle, muscle is heavier than fat, or between different types of fat.
    This does mean we can ignore obesity but as another recent article emphasised that as we age our dietary needs change. we should not be obsessed with body image.
    Moderation in everything is the key with a good balance in our diet and other lifestyle factors.
    11th Sep 2015
    correct the BMI is no longer a big deal
    11th Sep 2015
    Both my father in law & father developed forms of dementia, altzheimers or similar in their late 70's. Neither were over weight, were very active walkers & gardeners & ate well. Neither drank & only 1 smoked up to age 40. My father in law was never stressed & was happy go lucky. My Dad stressed a lot. I dont think they have any idea yet what causes it. I suspect preservatives, colouring & artificial flavouring - non of which we are meant to eat ! But who knows.
    Being overweight brings enough preobelems that everyone knows about already. Dont think this research will stop them overeating !
    11th Sep 2015
    So much reseRch coming out of the US is US! Is it causative or just present in some. Why repeat atrocious Amerucan research probably funded by big pharma until it's actually proven. Even then it will probably be wrong.
    11th Sep 2015
    So much reseRch coming out of the US is US! Is it causative or just present in some. Why repeat atrocious Amerucan research probably funded by big pharma until it's actually proven. Even then it will probably be wrong.
    Ageing but not getting old
    12th Sep 2015
    Renny: I suspect that the lifestyle we lead here in major Australian cities (except for our ability to get out & about for exercise activities in mostly all weather) is much the same as in the US. Certainly we read about increasing obesity/overweight, stress, increasing time spent sitting and/or in front of our various screens, etc. It's not too much of a stretch to think we may experience similar health results. And why is American research 'atrocious'? We have big pharma here also you know.
    11th Sep 2015
    So 10 per cent developed Alzheimer's. What about the 90 per cent overweight volunteers who didn't develop the desease. There is a lot of guessing going on
    25th Sep 2015
    If this is he case, how come I have known 5 people who have contracted Alzheimers and all have been average to slim in buile.
    30th Sep 2015
    It is a weird situation. Alzheimers patients regularly lose their memory, but I do not know the exact reason for this decease. In fact, the person who cares for an alzheimers patient needs to be treated with good care. We cannot live alone, then how can a person who loses memory gradually? By reading this article, what I knew that to keep ourself healthy. Obesity is the over existence of fat in out body. If we keep it balanced, then we can escape from Alzheimers, for a limit. I have done Master of public health as a distance education. Let me get involved in my society to make aware of this information and take classes on keeping our body healthy always.

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